Articles about Erection, erectile dysfunction, Viagra, Cialis, premature
ejaculation and other Men's health problems, How to Increase Sex Drive
and more.
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Diet
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Cialis Levitra, wich is the best medication for erectile dysfunction?
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About Viagra and Cialis drugs
The name Viagra is probably also derived from an Indian word,
Sanskrit "vyaghra" (tiger), although it is also an amalgamation
of Latin "vita" (life) and "Niagara" (the waterfall), perhaps
intentionally appropriate.
The name of the product resembles the Hindi word for "46", chhiyalis,
sometimes transliterated as chialis or cialis.
The history of Cialis cannot be discussed without mentioning
Viagra or Pfizer. The FDA's approval on March 27, 1998, lead both of these
prescription drugs, Viagra and Pfizer, to a ground breaking success
in just the first year of introduction as they sold drugs worth over a
billion dollars. However, things changed considerably for the two giants
of erectile dysfunction drugs when the FDA also approved Levitra
in August 19, 2003, and Cialis in November 21, 2003. In 1993 the
drug company Icos began studying IC351, which is a PDE5 enzyme inhibiter,
and this is basically the process through which the erectile dysfunction
drugs work. In 1994, Pfizer scientists discovered that Sildenafil Citrate,
which is a white crystalline powder that temporarily normalizes erectile
function of the penis by blocking an enzyme known to inhibit the production
of a chemical that causes erections, caused the heart patients that were
participating in a clinical study of a heart medicine to have erections.
Although the scientists were not testing the chemical compound IC351 for
erectile dysfunction, the compound seem to have a side effect which could
potentially worth million, if not billions. Soon Icos received its very
first patent in 1994 on IC351, and the clinical trials of phase I took
place in 1995. In 1997, phase II clinical studies began and Icos performed
its first study on patients with erectile dysfunction. Phase II lasted
about two years, and after that phase III began.
In 1998, ICOS Corporation, and Eli Lilly and Company, commercialized
the drug for erectile dysfunction, and two year later, they filed a new
drug application with the U.S. Food and Drug Admisnistration for IC351,
only difference was that this time they decided to call the drug, Cialis.
In May of 2002, Icos and Eli Lilly and Company reported to the American
Urological Association that the phase III tests show that Cialis
works for up to 36 hours, and one year later Icos and Eli Lilly and Company
received the U.S. FDA's approval for Cialis. One advantage that Cialis
has over Viagra is that Cialis works for up to 36 hours as compared to
4 hours for Viagra.
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